I have spina bifida and what this means to Malaysia

Authors

  • Noraishah Mydin Abdul-Aziz, PhD Invertebrate and Vertebrate Neurobiology Laboratory, Department of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.

DOI:

https://doi.org/10.31117/neuroscirn.v5i2.149

Keywords:

spina bifida, Malaysia, Neural Tube Defects

Abstract

In December of 2002, the Malaysian government sent one very highly opinionated individual with spina bifida to do her PhD on her medical condition at University College London (UCL). Truth be told, in retrospect, during the phone interview with Professor Andrew J. Copp, this particular Malaysian student was not aware that her would-be PhD supervisor at that time most likely may not have considered the extent of the severity of her disability and the extent of having to deal with an individual with needs, different from other postgraduate students. UCL and England, being champions of equal opportunity, the focus during the London-Kuala Lumpur phone interview was entirely on her laboratory experience. The individual knew one thing and one thing alone, that she wanted to be regarded as capable purely on the basis of her academic abilities, and keenness on the topic and that she knew she had a huge plus on her side, that the Malaysian government would finance her studies (being of Bumiputera status by virtue of her mother's ethnicity) and having passed all the relevant exams and that all she needed to do was to make the case to procure a PhD studentship from a top global university.

References

Abdul-Aziz, N. M., Turmaine, M., Greene, N. D. E., & Copp, A. J. (2009). Ephrina-EphA receptor interactions in mouse spinal neurulation: Implications for neural fold fusion. The International Journal of Developmental Biology, 53(4), 559–568. https://doi.org/10.1387/ijdb.082777na

Abdullah, N. L., Gunasekaran, R., Mohd-Zin, S. W., Lim, B.-H., Maniam, P., Mohd-Salleh, A. S., Thong, M.-K., Chik, Z., Nordin, N., Omar, Z., Engkasan, J. P., Ganesan, D., Aiezzah, Z. N., Ahmad-Annuar, A., & Abdul-Aziz, N. M. (2018). Cranial neural tube defect after trimethoprim exposure. BMC Research Notes, 11(1), 475. https://doi.org/10.1186/s13104-018-3593-1

Abdullah, N. L., Mohd-Zin, S. W., Ahmad-Annuar, A., & Abdul-Aziz, N. M. (2017). A novel occulta-type spina bifida mediated by murine double heterozygotes EPHA2 and EphA4 receptor tyrosine kinases. Frontiers in Cell and Developmental Biology, 5, 105. https://doi.org/10.3389/fcell.2017.00105

Al-Ali, M., Salman, G., Rasheed, A., Al-Ani, G., Al-Rubaiy, S., Alwan, A., & Al-Shaikli, A. (1999). Phenoxybenzamine in the management of neuropathic bladder following spinal cord injury. ANZ Journal of Surgery, 69(9), 660–663. https://doi.org/10.1046/j.1440-1622.1999.01659.x

Alimi, Y., Iwanaga, J., Oskouian, R. J., Loukas, M., & Tubbs, R. S. (2018). Intelligence quotient in patients with myelomeningocele: A Review. Cureus 10(8), e3137. https://doi.org/10.7759/cureus.3137

Arain, M., Haque, M., Johal, L., Mathur, P., Nel, W., Rais, A., Sandhu, R., & Sharma S. (2013). Maturation of the adolescent brain. Neuropsychiatric Disease and Treatment, 9, 449-461. https://doi.org/10.2147/ndt.s39776

Ashwal, S., & Rust, R. (2003). Child neurology in the 20th Century. Pediatric Research, 53(2), 345–361. https://doi.org/10.1203/01.pdr.0000047655.66475.52

Auffret, M., Cottin, J., Vial, T., & Cucherat, M. (2019). Clomiphene citrate and neural tube defects: A meta‐analysis of controlled observational studies. BJOG: An International Journal of Obstetrics & Gynaecology, 126(9), 1127–1133. https://doi.org/10.1111/1471-0528.15800

Averbeck, M. A., & Madersbacher, H. (2015). Follow-up of the Neuro-Urological Patient: A systematic review. BJU International, 115, 39–46. https://doi.org/10.1111/bju.13084

Azar, R., & Shadpour, P. (2016). in vivo trial of a novel atraumatic urinary catheter design for prevention of catheter-induced trauma. Journal of Endourology, 30(7), 822–827. https://doi.org/10.1089/end.2015.0827

Bandy, L., Adhikari, V., Jebb, S., & Rayner, M. (2019). The use of commercial food purchase data for Public Health Nutrition Research: A systematic review. PLOS ONE, 14(1), e0210192. https://doi.org/10.1371/journal.pone.0210192

Bannink, F., Idro, R., & Van Hove, G. (2016). Parental stress and support of parents of children with spina bifida in Uganda. African Journal of Disability, 5(1), a225. https://doi.org/10.4102/ajod.v5i1.225

Boo, N.-Y., Cheah, I. G., & Thong, M.-K. (2013). Neural tube defects in Malaysia: Data from the Malaysian National Neonatal Registry. Journal of Tropical Pediatrics, 59(5), 338–342. https://doi.org/10.1093/tropej/fmt026

Botto, L. D., Moore, C. A., Khoury, M. J., & Erickson, J. D. (1999). Neural-tube defects. New England Journal of Medicine, 341(20), 1509–1519. https://doi.org/10.1056/nejm199911113412006

Braima, K. A., Muslimin, M., M. Ghazali, A.-R., Wan-Nor, F., Wilson, J. J., Jeffery, J., & Abdul-Aziz, N. M. (2017). Feeding behavior of mimomyia (etorleptiomyia) Luzonensis (Ludlow, 1905) (Diptera, Culicidae) in Peninsular Malaysia. Acta Tropica, 171, 138–140. https://doi.org/10.1016/j.actatropica.2017.03.025

Braima, K. A., Sum, J.-S., Ghazali, A.-R. M., Muslimin, M., Jeffery, J., Lee, W.-C., Shaker, M. R., Elamin, A.-E. M., Jamaiah, I., Lau, Y.-L., Rohela, M., Kamarulzaman, A., Sitam, F., Mohd-Noh, R., & Abdul-Aziz, N. M. (2013). Is there a risk of suburban transmission of malaria in Selangor, Malaysia? PLoS ONE, 8(10), e77924. https://doi.org/10.1371/journal.pone.0077924

Burnei, G., Gavriliu, S., Vlad, C., Georgescu, I., Ghita, R. A., Dughilă, C., Japie, E. M., & Onilă, A. (2015). Congenital scoliosis: an up-to-date. Journal of Medicine and Life, 8(3), 388–397.

Calloni, S. F., Huisman, T. A. G. M., Poretti, A., & Soares, B. P. (2017). Back pain and scoliosis in children: When to image, what to consider. The Neuroradiology Journal, 30(5), 393–404. https://doi.org/10.1177/1971400917697503

Camerer, E., Barker, A., Duong, D. N., Ganesan, R., Kataoka, H., Cornelissen, I., Darragh, M. R., Hussain, A., Zheng, Y.-W., Srinivasan, Y., Brown, C., Xu, S.-M., Regard, J. B., Lin, C.-Y., Craik, C. S., Kirchhofer, D., & Coughlin, S. R. (2010). Local protease signaling contributes to neural tube closure in the mouse embryo. Developmental Cell, 18(1), 25–38. https://doi.org/10.1016/j.devcel.2009.11.014

Cheung, K. M., Wang, T., Qiu, G. X., & Luk, K. D. (2007). Recent advances in the Aetiology of adolescent idiopathic scoliosis. International Orthopaedics, 32(6), 729–734. https://doi.org/10.1007/s00264-007-0393-y

Conti, D. V., Darst, B. F., Moss, L. C., Saunders, E. J., Sheng, X., Chou, A., Schumacher, F. R., Olama, A. A., Benlloch, S., Dadaev, T., Brook, M. N., Sahimi, A., Hoffmann, T. J., Takahashi, A., Matsuda, K., Momozawa, Y., Fujita, M., Muir, K., Lophatananon, A., … Haiman, C. A. (2021). Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nature Genetics, 53(1), 65–75. https://doi.org/10.1038/s41588-020-00748-0

Copp, A. J., Adzick, N. S., Chitty, L. S., Fletcher, J. M., Holmbeck, G. N., & Shaw, G. M. (2015). Spina bifida. Nature Reviews Disease Primers, 1(1). https://doi.org/10.1038/nrdp.2015.7

Copp, A. J., Brook, F. A., Peter Estibeiro, J., Shum, A. S. W., & Cockroft, D. L. (1990). The embryonic development of mammalian neural tube defects. Progress in Neurobiology, 35(5), 363–403. https://doi.org/10.1016/0301-0082(90)90037-h

Copp, A. J., Greene, N. D., & Murdoch, J. N. (2003). The genetic basis of mammalian neurulation. Nature Reviews Genetics, 4(10), 784–793. https://doi.org/10.1038/nrg1181

Copp, A. J., Stanier, P., & Greene, N. D. E. (2013). Neural tube defects: Recent advances, unsolved questions, and controversies. The Lancet Neurology, 12(8), 799–810. https://doi.org/10.1016/s1474-4422(13)70110-8

Daalen-Smith, C. V. (2007). ‘my mom was my left arm’: The lived experience of ableism for girls with Spina Bifida. Contemporary Nurse, 23(2), 262–273. https://doi.org/10.5172/conu.2006.23.2.262

Dell'Edera, D., Sarlo, F., Allegretti, A., Epifania, A. A., Simone, F., Lupo, M. G., Benedetto, M., D’apice, M.R., Capalbo, A. (2017). Prevention of neural tube defects and maternal gestational diabetes through the inositol supplementation: preliminary results. European Review for Medical and Pharmacological Sciences, 21(14), 3305–3311.

Devakumar, D., Bamford, A., Ferreira, M. U., Broad, J., Rosch, R. E., Groce, N., Breuer, J., Cardoso, M. A., Copp, A. J., Alexandre, P., Rodrigues, L. C., & Abubakar, I. (2018). Infectious causes of microcephaly: Epidemiology, pathogenesis, diagnosis, and Management. The Lancet Infectious Diseases, 18(1), e1–e13. https://doi.org/10.1016/s1473-3099(17)30398-5

Dewan, M. C., & Wellons, J. C. (2019). Fetal surgery for spina bifida. Journal of Neurosurgery: Pediatrics, 24(2), 105–114. https://doi.org/10.3171/2019.4.peds18383

Dominy, C. L., Arvind, V., Tang, J. E., Bellaire, C. P., Pasik, S. D., Kim, J. S., & Cho, S. K. (2021). Scoliosis surgery in social media: A Natural Language Processing Approach to analyzing the online patient perspective. Spine Deformity, 10(2), 239–246. https://doi.org/10.1007/s43390-021-00433-0

Esposito, D. B., Parker, S. E., Mitchell, A. A., Tinker, S. C., & Werler, M. M. (2021). Periconceptional nonsteroidal anti‐inflammatory drug use, folic acid intake, and the risk of Spina Bifida. Birth Defects Research, 113(17), 1257–1266. https://doi.org/10.1002/bdr2.1944

Eswara, J. R., Castellan, M., González, R., Mendieta, N., & Cendron, M. (2018). The urological management of children with Spinal Cord Injury. World Journal of Urology, 36(10), 1593–1601. https://doi.org/10.1007/s00345-018-2433-1

Ewalt, D. H., & Allen, T. D. (1996). Urinary tract reconstruction in children undergoing renal transplantation. Advances in Renal Replacement Therapy, 3(1), 69–76. https://doi.org/10.1016/s1073-4449(96)80042-2

Feldman, D. E., Swaine, B., Gosselin, J., Meshefedjian, G., & Grilli, L. (2008). Is waiting for rehabilitation services associated with changes in function and quality of life in children with physical disabilities? Physical & Occupational Therapy In Pediatrics, 28(4), 291–304. https://doi.org/10.1080/01942630802224868

Fernbach, S. K., & Davis, T. M. (1986). The abnormal renal axis in children with spina bifida and gibbus deformity—the pseudohorseshoe kidney. Journal of Urology, 136(6), 1258–1260. https://doi.org/10.1016/s0022-5347(17)45307-9

Flanagan, A., Kelly, E. H., & Vogel, L. C. (2013). Psychosocial outcomes of children and adolescents with early-onset spinal cord injury and those with spina bifida. Pediatric Physical Therapy, 25(4), 452–459. https://doi.org/10.1097/pep.0b013e3182a5d35c

Furtado, L. M., da Costa Val Filho, J. A., Holliday, J. B., da Silva Costa, J., de Matos, M. A., Nascimento, V. A., & Ramos Cavalcanti, T. (2020). Endoscopic third ventriculostomy in patients with myelomeningocele after shunt failure. Child's Nervous System, 36(12), 3047–3052. https://doi.org/10.1007/s00381-020-04596-5

Gunasekaran, R., Shaker, M. R., Mohd-Zin, S. W., Abdullah, A., Ahmad-Annuar, A., & Abdul-Aziz, N. M. (2017). Maternal intake of dietary virgin coconut oil modifies essential fatty acids and causes low body weight and spiky fur in mice. BMC Complementary and Alternative Medicine, 17(1), 79. https://doi.org/10.1186/s12906-017-1600-z

Gupta, G., Heary, R. F., & Michaels, J. (2010). Reversal of longstanding neurological deficits after a late release of Tethered Spinal Cord. Neurosurgical Focus, 29(1), e11. https://doi.org/10.3171/2010.3.focus1078

Halim-Fikri, H., Etemad, A., Latif, A. Z., Merican, A. F., Baig, A. A., Annuar, A. A., Ismail, E., Salahshourifar, I., Liza-Sharmini, A. T., Ramli, M., Shah, M. I., Johan, M. F., Hassan, N. N., Abdul-Aziz, N. M., Noor, N. H., Nur-Shafawati, A. R., Hassan, R., Bahar, R., Zain, R. B., … Zilfalil, B. A. (2015). The first Malay database toward the ethnic-specific target molecular variation. BMC Research Notes, 8(1), 176. https://doi.org/10.1186/s13104-015-1123-y

Harris, M. J., & Juriloff, D. M. (2010). An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure. Birth Defects Research Part A: Clinical and Molecular Teratology, 88(8), 653–669. https://doi.org/10.1002/bdra.20676

Hay, W. W. (2011). Care of the infant of the diabetic mother. Current Diabetes Reports, 12(1), 4–15. https://doi.org/10.1007/s11892-011-0243-6

Ivanyi, B., Schoenmakers, M., van Veen, N., Maathuis, K., Nollet, F., & Nederhand, M. (2015). The effects of orthoses, footwear, and walking aids on the walking ability of children and adolescents with spina bifida. Prosthetics & Orthotics International, 39(6), 437–443. https://doi.org/10.1177/0309364614543550

Jacobson, A. G., & Moury, J. D. (1995). Tissue boundaries and cell behavior during neurulation. Developmental Biology, 171(1), 98–110. https://doi.org/10.1006/dbio.1995.1263

Jeffery, J., Sulaiman, S., Oothuman, P., Vellayan, S., Zainol-Ariffin, P., Paramaswaran, S., Razak, A., Muslimin, M., Kamil-Ali, O.B., Rohela, M. and Abdul-Aziz, N.M. (2012) Domiciliary cockroaches found in restaurants in five zones of Kuala Lumpur federal territory, peninsular Malaysia. Tropical Biomedicine, 29(1), 180–186.

Johnson, A. F., Nguyen, H. T., & Veitia, R. A. (2019). Causes and effects of haploinsufficiency. Biological Reviews, 94(5), 1774–1785. https://doi.org/10.1111/brv.12527

Kanaheswari, Y., Razak, N. N., Chandran, V., & Ong, L. C. (2010). Predictors of parenting stress in Mothers of children with Spina Bifida. Spinal Cord, 49(3), 376–380. https://doi.org/10.1038/sc.2010.125

Kancherla, V., Walani, S. R., Weakland, A. P., Bauwens, L., Oakley, G. P., & Warf, B. C. (2017). Scorecard for Spina bifida research, prevention, and policy – a development process. Preventive Medicine, 99, 13–20. https://doi.org/10.1016/j.ypmed.2017.01.022

Kaye, I. Y., Payan, M., & Vemulakonda, V. M. (2016). Association between clean intermittent catheterization and urinary tract infection in infants and toddlers with spina bifida. Journal of Pediatric Urology, 12(5), P284.E1-284.E6. https://doi.org/10.1016/j.jpurol.2016.02.010

Kelly, N. C., Ammerman, R. T., Rausch, J. R., Ris, M. D., Yeates, K. O., Oppenheimer, S. G., & Enrile, B. G. (2012). Executive functioning and psychological adjustment in children and Youth With Spina Bifida. Child Neuropsychology, 18(5), 417–431. https://doi.org/10.1080/09297049.2011.613814

Khitamy, B. A. (2013). Divergent views on abortion and the period of ensoulment. Sultan Qaboos University Medical Journal, 13(1), 26.–31. https://doi.org/10.12816/0003192

Lapides, J., Diokno, A. C., Silber, S. J., & Lowe, B. S. (1972). Clean, intermittent self-catheterization in the treatment of urinary tract disease. Journal of Urology, 107(3), 458–461. https://doi.org/10.1016/s0022-5347(17)61055-3

Lin, S., Munsie, J. P., Herdt-Losavio, M. L., Druschel, C. M., Campbell, K., Browne, M. L., Romitti, P. A., Olney, R. S., & Bell, E. M. (2012). Maternal asthma medication use and the risk of selected birth defects. Pediatrics, 129(2), e317–e324. https://doi.org/10.1542/peds.2010-2660

Lindsay, S., McPherson, A. C., & Maxwell, J. (2016). Perspectives of School-work transitions among youth with spina bifida, their parents and health care providers. Disability and Rehabilitation, 39(7), 641–652. https://doi.org/10.3109/09638288.2016.1153161

Lomax-Bream, L. E., Barnes, M., Copeland, K., Taylor, H. B., & Landry, S. H. (2007). The impact of Spina Bifida on development across the first 3 years. Developmental Neuropsychology, 31(1), 1–20. https://doi.org/10.1207/s15326942dn3101_1

Lowe, L. H., Johanek, A. J., & Moore, C. W. (2007). Sonography of the neonatal spine: Part 2, Spinal Disorders. American Journal of Roentgenology, 188(3), 739–744. https://doi.org/10.2214/ajr.05.2160

Madersbacher, S., Schmidt, J., Eberle, J., Thoeny, H., Burkhard, F., Hochreiter, W., & Studer, U. (2003). Long-term outcome of Ileal Conduit diversion. Journal of Urology, 169(3), 985–990. https://doi.org/10.1097/01.ju.0000051462.45388.14

Mancarella, C., Delfini, R., & Landi, A. (2019). Chiari malformations. Acta Neurochirurgica Supplement, 125, 89–95. https://doi.org/10.1007/978-3-319-62515-7_13

Maniou, E., Staddon, M. F., Marshall, A. R., Greene, N. D., Copp, A. J., Banerjee, S., & Galea, G. L. (2021). Hindbrain neuropore tissue geometry determines asymmetric cell-mediated closure dynamics in mouse embryos. Proceedings of the National Academy of Sciences, 118(19), e2023163118. https://doi.org/10.1073/pnas.2023163118

Mansor, N. I., Ntimi, C. M., Abdul-Aziz, N. M., Ling, K.-H., Adam, A., Rosli, R., Hassan, Z., & Nordin, N. (2020). Asymptomatic neurotoxicity of amyloid β-peptides (AΒ1-42 and aβ25-35) on mouse embryonic stem cell-derived neural cells. Bosnian Journal of Basic Medical Sciences, 21(1), 98 –110. https://doi.org/10.17305/bjbms.2020.4639

Martín-Crespo Izquierdo, R., Luque Mialdea, R., Cerdá Berrocal, J., & Arrojo Vila, F. (1995). [Indications for urodynamic studies in childhood: our experience with 214 surgical patients]. Cirugia Pediatrica, 8(1), 31-36.

Mattei, J.-F. (2018). Respecting the patient's autonomy . Soins, 63(824), 25–27. https://doi.org/10.1016/j.soin.2018.02.004

McKibben, M. J., Seed, P., Ross, S. S., & Borawski, K. M. (2015). Urinary tract infection and neurogenic bladder. Urologic Clinics of North America, 42(4), 527–536. https://doi.org/10.1016/j.ucl.2015.05.006

Mohd Zain, S. N., Syed Khalil Amdan, S. A., Braima, K. A., Abdul-Aziz, N. M., Wilson, J.-J., Sithambaran, P., & Jeffery, J. (2015). Ectoparasites of Murids in Peninsular Malaysia and their associated diseases. Parasites & Vectors, 8(1), 254. https://doi.org/10.1186/s13071-015-0850-1

Mohd-Zin, S. W., Abdullah, N.-L., Abdullah, A., Greene, N. D. E., Cheah, P.-S., Ling, K.-H., Yusof, H., Marwan, A. I., Williams, S. M., York, K. T., Ahmad-Annuar, A., & Abdul-Aziz, N. M. (2016). Identification of the genomic mutation in epha4 (rb-2J/rb-2j) mice. Genome, 59(7), 439–448. https://doi.org/10.1139/gen-2015-0142

Mohd-Zin, S. W., Marwan, A. I., Abou Chaar, M. K., Ahmad-Annuar, A., & Abdul-Aziz, N. M. (2017). Spina bifida: Pathogenesis, mechanisms, and genes in mice and humans. Scientifica, 2017, 1–29. https://doi.org/10.1155/2017/5364827

Mokhtar, A. S., Braima, K. A., Peng Chin, H., Jeffery, J., Mohd Zain, S. N., Rohela, M., Lau, Y. L., Jamaiah, I., Wilson, J.-J., & Abdul-Aziz, N. M. (2016). Intestinal myiasis in a Malaysian patient caused by larvae ofclogmia albipunctatus(diptera: Psychodidae). Journal of Medical Entomology, 53(4), 957–960. https://doi.org/10.1093/jme/tjw014

Mokhtar, A. S., Sridhar, G. S., Mahmud, R., Jeffery, J., Lau, Y. L., Wilson, J.-J., & Abdul-Aziz, N. M. (2016). First case report of canthariasis in an infant caused by the larvae oflasioderma serricorne(coleoptera: Anobiidae). Journal of Medical Entomology, 53(5), 1234–1237. https://doi.org/10.1093/jme/tjw071

Moury, J. D., & Schoenwolf, G. C. (1995). Cooperative model of epithelial shaping and bending during avian neurulation: Autonomous movements of the neural plate, autonomous movements of the epidermis, and interactions in the neural plate/epidermis transition zone. Developmental Dynamics, 204(3), 323–337. https://doi.org/10.1002/aja.1002040310

Mummareddy, N., Dewan, M. C., Mercier, M. R., Naftel, R. P., Wellons, J. C., & Bonfield, C. M. (2017). Scoliosis in myelomeningocele: Epidemiology, management, and functional outcome. Journal of Neurosurgery: Pediatrics, 20(1), 99–108. https://doi.org/10.3171/2017.2.peds16641

Muslimin, M., Wilson, J.-J., Ghazali, A.-R. M., Braima, K. A., Jeffery, J., Wan-Nor, F., Alaa-Eldin, M. E., Mohd-Zin, S.-W., Wan-Yusoff, W. S., Norma-Rashid, Y., Lau, Y. L., Rohela, M., & Abdul-Aziz, N. M. (2015). First report of brown widow spider sightings in Peninsular Malaysia and notes on its global distribution. Journal of Venomous Animals and Toxins Including Tropical Diseases, 21, 1-8. https://doi.org/10.1186/s40409-015-0010-2

Naufal, Z., Zhiwen, L., Zhu, L., Zhou, G. O.-D., McDonald, T., He, L. Y., Mitchell, L., Ren, A., Zhu, H., Finnell, R., & Donnelly, K. C. (2009). Biomarkers of exposure to combustion by-products in a human population in Shanxi, China. Journal of Exposure Science & Environmental Epidemiology, 20(4), 310–319. https://doi.org/10.1038/jes.2009.19

Oakeshott, P., & Hunt, G. M. (1991). Carbamazepine and spina bifida. British Medical Journal, 303(6803), 651–651. https://doi.org/10.1136/bmj.303.6803.651-b

Ong, L. C., Sofiah A. (2002). Malaysian children with spina bifida: relationship between functional outcome and level of lesion. Singapore Medical Journal, 43(1), 12–7.

Ong, L. C., Norshireen, N. A. R., & Chandran, V. (2010a). A comparison of parenting stress between Mothers of children with spina bifida and able bodied controls. Fluids Barriers CNS, 7, S28. https://doi.org/10.1186/1743-8454-7-s1-s28

Ong, L. C., Norshireen, N. A. R., & Chandran, V. (2010b). Maternal Mental Health in families of children with Spina Bifida. World Journal of Pediatrics, 7(1), 54–59. https://doi.org/10.1007/s12519-011-0246-z

Ong, L. C., Norshireen, N. A., & Chandran, V. (2011). A comparison of parenting stress between Mothers of children with spina bifida and able-bodied controls. Developmental Neurorehabilitation, 14(1), 22–28. https://doi.org/10.3109/17518423.2010.523057

Ortiz‐Cruz, G., Aguayo‐Gómez, A., Luna‐Muñoz, L., Muñoz‐Téllez, L. A., & Mutchinick, O. M. (2021). Myelomeningocele genotype–phenotype correlation findings in cilia, HH, PCP, and Wnt signaling pathways. Birth Defects Research, 113(4), 371–381. https://doi.org/10.1002/bdr2.1872

Padmanabhan, R. (2006). Etiology, pathogenesis and prevention of neural tube defects. Congenital Anomalies, 46(2), 55–67. https://doi.org/10.1111/j.1741-4520.2006.00104.x

Pai, Y.-J., Abdullah, N. L., Mohd.-Zin, S. W., Mohammed, R. S., Rolo, A., Greene, N. D. E., Abdul-Aziz, N. M., & Copp, A. J. (2012). Epithelial fusion during neural tube morphogenesis. Birth Defects Research Part A: Clinical and Molecular Teratology, 94(10), 817–823. https://doi.org/10.1002/bdra.23072

Pit-ten Cate, I. M., Kennedy, C., & Stevenson, J. (2002). Disability and quality of life in Spina Bifida and hydrocephalus. Developmental Medicine & Child Neurology, 44(05), 317–322. https://doi.org/10.1111/j.1469-8749.2002.tb00818.x

Pyrgaki, C., Trainor, P., Hadjantonakis, A.-K., & Niswander, L. (2010). Dynamic imaging of mammalian neural tube closure. Developmental Biology, 344(2), 941–947. https://doi.org/10.1016/j.ydbio.2010.06.010

Rahmad, S. N., Valentino, A., & Masdar, H. (2021). Gambaran Kasus Spina Bifida di RSUD Arifin Achmad Provinsi Riau Periode 2015-2017. Jurnal Ilmu Kedokteran, 14(1), 52–58.

Repko, M., Krbec, M., Chaloupka, R., Tichy, V., & Sprlakova-Pukova, A. (2008). [Neuromuscular deformity of the pelvis and its surgical treatment]. Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca, 75(2), 117–122.

Riddle, S., Meinzen-Derr, J., Tabangin, M., Woodward, J., & Wiley, S. (2019). Emergency department utilization among Pediatric Spina Bifida patients. Journal of Pediatric Rehabilitation Medicine, 12(4), 375–381. https://doi.org/10.3233/prm-180561

Rodriguez, V. V., Tello, C. A., Piantoni, L., Wilson, I. A., Galareto, E., Remondino, R. G., Bersusky, S. E., Davies, R., & Noel, M. A. (2021). Chiari 1: Is decompression always necessary previous to scoliosis surgery? Spine Deformity, 9(5), 1253–1258. https://doi.org/10.1007/s43390-021-00336-0

Rossi, A., Biancheri, R., Cama, A., Piatelli, G., Ravegnani, M., & Tortori-Donati, P. (2004). Imaging in spine and spinal cord malformations. European Journal of Radiology, 50(2), 177–200. https://doi.org/10.1016/j.ejrad.2003.10.015

Royo-Salvador, M. B., Fiallos-Rivera, M. V., Salca, H. C., & Ollé-Fortuny, G. (2020). The filum disease and the neuro-cranio-vertebral syndrome: Definition, clinical picture and imaging features. BMC Neurology, 20(1), 175. https://doi.org/10.1186/s12883-020-01743-y

Sahmat, A., Gunasekaran, R., Mohd-Zin, S. W., Balachandran, L., Thong, M.-K., Engkasan, J. P., Ganesan, D., Omar, Z., Azizi, A. B., Ahmad-Annuar, A., & Abdul-Aziz, N. M. (2017). The prevalence and distribution of spina bifida in a single major referral center in Malaysia. Frontiers in Pediatrics, 5, 237. https://doi.org/10.3389/fped.2017.00237

Sakurai, T., Dorr, N. P., Takahashi, N., McInnes, L. A., Elder, G. A., & Buxbaum, J. D. (2010). Haploinsufficiency of Gtf2i, a gene deleted in Williams syndrome, leads to increases in social interactions. Autism Research, 4(1), 28–39. https://doi.org/10.1002/aur.169

Sarris, C. E., Tomei, K. L., Carmel, P. W., & Gandhi, C. D. (2012). Lipomyelomeningocele: Pathology, treatment, and outcomes. Neurosurgical Focus, 33(4), e3. https://doi.org/10.3171/2012.7.focus12224

Scarberry, K. A., Gor, R. A., & Kovell, R. C. (2021). Management of the transitional urology patient: The role of the adult reconstructive urologist. Current Urology Reports, 22, 15. https://doi.org/10.1007/s11934-021-01035-z

Schacter, B., Weitkamp, L. R., & Johnson, W. E. (1984). Parental HLA compatibility, fetal wastage and neural tube defects: evidence for a T/t-like locus in humans. Americal Journal Of Human Genetics, 36(5), 1082–1091.

Schneider, J., Mohr, N., Aliatakis, N., Seidel, U., John, R., Promnitz, G., Spors, B., & Kaindl, A. M. (2020). Brain malformations and cognitive performance in Spina Bifida. Developmental Medicine & Child Neurology, 63(3), 295–302. https://doi.org/10.1111/dmcn.14717

Seitzberg, A., Lind, M., & Biering-Sørensen, F. (2007). Ambulation in adults with myelomeningocele. is it possible to predict the level of ambulation in early life? Child's Nervous System, 24(2), 231–237. https://doi.org/10.1007/s00381-007-0450-2

Soekirman, & Jus'at, I. (2017). Food fortification in Indonesia. Malaysian Journal of Nutrition, 23(1), 1–7.

Sum, J.-S., Lee, W.-C., Amir, A., Braima, K. A., Jeffery, J., Abdul-Aziz, N. M., Fong, M.-Y., & Lau, Y.-L. (2014). Phylogenetic study of six species of anopheles mosquitoes in Peninsular Malaysia based on inter-transcribed spacer region 2 (ITS2) of ribosomal DNA. Parasites & Vectors, 7(1), 309. https://doi.org/10.1186/1756-3305-7-309

Szabo, R., Hobson, J. P., Christoph, K., Kosa, P., List, K., & Bugge, T. H. (2009). Regulation of cell surface protease matriptase by Hai2 is essential for placental development, neural tube closure and embryonic survival in mice. Development, 136(15), 2653–2663. https://doi.org/10.1242/dev.038430

Tam, J. Z., Darus, A., Mohamed, Z., Jamaluddin, N., & Mohammed, M.A.A. (2020). BACKS 2020: Criteria for Occupational Spine Disease in a Social Security Compensation System. In: Karwowski, W., Goonetilleke, R., Xiong, S., Goossens, R., Murata, A. (eds) Advances in Physical, Social & Occupational Ergonomics. AHFE 2020. Advances in Intelligent Systems and Computing, vol 1215. Springer, Cham. https://doi.org/10.1007/978-3-030-51549-2_20

Tao, L., Zhou, S., Tao, Z., Wen, K., Da, W., Meng, Y., & Zhu, Y. (2020). The publication trends and hot spots of scoliosis research from 2009 to 2018: A 10-year bibliometric analysis. Annals of Translational Medicine, 8(6), 365–365. https://doi.org/10.21037/atm.2020.02.67

Thong, P. L., Wong, S. W., Abdul Manaf, M. R., Lee, M. L., & Kanaheswari, Y. (2019). Health-related quality of life in paediatric spina bifida. Medical Journal of Malaysia, 74(4), 281–287.

Tomás, C., Oliveira, E., Sousa, D., Uba-Chupel, M., Furtado, G., Rocha, C., Teixeira, A., Ferreira, P., Alves, C., Gisin, S., Catarino, E., Carvalho, N., Coucelo, T., Bonfim, L., Silva, C., Franco, D., González, J. A., Jardim, H. G., Silva, R., … Rosa, R. S. (2016). Proceedings of the 3rd IPLeiria’s International Health Congress. BMC Health Services Research, 16(3), 200. https://doi.org/10.1186/s12913-016-1423-5

Trudell, A., & Odibo, A. (2014). Diagnosis of spina bifida on ultrasound: Always termination?. Best Practice & Research. Clinical Obstetrics & Gynaecology, 28(3), 367-377. https://doi.org/10.1016/j.bpobgyn.2013.10.006

Tseng, J., Kuo, M., Kwang Tu, Y., & Tseng, M. (2008). Outcome of untethering for symptomatic spina bifida occulta with lumbosacral spinal cord tethering in 31 patients: analysis of preoperative prognostic factors. The Spine Journal, 8(4), 630-638. https://doi.org/10.1016/j.spinee.2005.11.005

Tully, H., & Dobyns, W. (2014). Infantile hydrocephalus: A review of epidemiology, classification and causes. European Journal Of Medical Genetics, 57(8), 359-368. https://doi.org/10.1016/j.ejmg.2014.06.002

University of California San Diego Health (2020). New Grant Seeks to Fill Knowledge Gaps Regarding Spina Bifida. Accessed 16 March 2022, https://www.newswise.com/articles/new-grant-seeks-to-fill-knowledge-gaps-regarding-spina-bifida

Van Kerrebroeck, P. E. V. (1998). The role of electrical stimulation in voiding dysfunction. European Urology, 34(Suppl. 1), 27–30. https://doi.org/10.1159/000052272

Van Noorden, R., & Singh Chawla, D. (2019). Hundreds of extreme self-citing scientists revealed in new database. Nature, 572(7771), 578–579. https://doi.org/10.1038/d41586-019-02479-7

Vellayan, S., Jeffery, J., Oothuman, P., Zahedi, M., Krishnasamy, M., Paramaswaran, S., Rohela, M ., & Abdul-Aziz, N. M. (2012). Oxyspiruriasis in zoo birds. Tropical Biomedicine, 29(2), 304-307.

Vialle, R., Thévenin-Lemoine, C., & Mary, P. (2013). Neuromuscular scoliosis. Orthopaedics & Traumatology: Surgery & Research, 99(1), s124-s139. https://doi.org/10.1016/j.otsr.2012.11.002

Việt, N. D. (2021). [Study on pathological characteristics and results of clean intermittent catheterization for neurocysticercosis in patients after medullary medullary surgery]. Ha Noi Medical University

Vinck, A. (2006). Arnold-Chiari-II malformation and cognitive functioning in spina bifida. Journal of Neurology, Neurosurgery & Psychiatry, 77(9), 1083–1086. https://doi.org/10.1136/jnnp.2005.075887

Wallingford, J. B., Niswander, L. A., Shaw, G. M., & Finnell, R. H. (2013). The continuing challenge of understanding, preventing, and treating neural tube defects. Science, 339(6123), 1222002. https://doi.org/10.1126/science.1222002

Welbourn, H. (1975). Spina bifida children attending ordinary schools. British Medical Journal, 1(5950), 142–145. https://doi.org/10.1136/bmj.1.5950.142

Westney, O. L. (2010). The neurogenic bladder and incontinent urinary diversion. Urologic Clinics of North America, 37(4), 581–592. https://doi.org/10.1016/j.ucl.2010.07.003

Wiener, J. S., Suson, K. D., Castillo, J., Routh, J. C., Tanaka, S. T., Liu, T., Ward, E. A., Thibadeau, J. K., & Joseph, D. B. (2018). Bladder management and continence outcomes in adults with spina bifida: Results from the National Spina Bifida Patient Registry, 2009 to 2015. Journal of Urology, 200(1), 187–194. https://doi.org/10.1016/j.juro.2018.02.3101

Wu, H.-Y. (2010). Achieving urinary continence in children. Nature Reviews Urology, 7(7), 371–377. https://doi.org/10.1038/nrurol.2010.78

Yaltırık, K., El Tecle, N. E., Pierson, M. J., Puryear, A., Atalay, B., & Elbabaa, S. K. (2017). Management of concomitant scoliosis and tethered cord syndrome in non-spina bifida pediatric population. Child's Nervous System, 33(11), 1899–1903. https://doi.org/10.1007/s00381-017-3504-0

Zimmermann, M., Seifert, V., Trantakis, C., & Raabe, A. (2001). Open MRI-guided microsurgery of intracranial tumours in or near eloquent brain areas. Acta Neurochirurgica, 143(4), 327–337. https://doi.org/10.1007/s007010170086

Zoghi, S., Feili, M., Mosayebi, M. A., Afifi, M. A., Feili, A., Masoudi, M. S., & Taheri, R. (2021). Surgical Outcomes of Myelomeningocele Repair: a 20-Year Experience from a Single Center in a Middle-Income Country. MedRxiv, 2021.11.07.21266030. https://doi.org/10.1101/2021.11.07.21266030

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2022-06-26

How to Cite

Abdul-Aziz, N. M. (2022). I have spina bifida and what this means to Malaysia. Neuroscience Research Notes, 5(2), 149. https://doi.org/10.31117/neuroscirn.v5i2.149

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