Beyond survival: cognitive, linguistic, and quality-of-life outcomes after an out-of-hospital cardiac arrest in a neurologically complex patient
DOI:
https://doi.org/10.31117/neuroscirn.v9i3.550Keywords:
cardiac arrest, hypoxic brain injury, cognitive function, cognitive impairment, cognitionAbstract
Out-of-hospital cardiac arrest (OHCA) often results in hypoxic–ischemic brain injury with persistent neurocognitive sequelae that may not be fully captured by routine neuroimaging. We report a detailed neuropsychological and language profile of a 32-year-old Greek-speaking Cypriot male assessed six months after OHCA. The case was neurologically complex, as the patient had a history of right frontal traumatic brain injury, chronic right frontal gliosis, post-traumatic epilepsy, and long-term antiepileptic treatment prior to the OHCA. A standardized, culturally appropriate battery with qualitative analysis assessed attention, processing speed, executive functions, memory, language, and visuospatial abilities, alongside mood and quality of life. Findings showed a heterogeneous pattern, including severe impairments in verbal episodic memory and moderate-to-severe executive dysfunction, mild attentional inefficiency, and relatively preserved visuospatial skills and nonverbal memory. Language performance was characterized by impaired lexical access and discourse/narrative organization, consistent with executive–linguistic interaction. The profile was interpreted cautiously as potentially reflecting interacting contributions from post-arrest hypoxic-ischemic vulnerability, pre-existing frontal pathology, epilepsy-related factors, and medication effects. Patient reported outcomes indicated preserved emotional well-being and satisfactory quality of life. This case underscores the value of early cognitive-linguistic and psychosocial screening following OHCA and supports multidisciplinary follow-up assessment to identify impairments affecting communication, activity, and participation. To our knowledge, this is the first detailed post-OHCA neuropsychological characterization of a Greek speaking Cypriot patient, highlighting the need for culturally and linguistically tailored assessment. This contributes data to an underrepresented population and suggests priority targets for intervention.
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Copyright (c) 2026 Marianna Christodoulou Devledian, Astero Constantinou, Tasos Tsokkos, Tonia Flerry Artemi, Andria Lori, Elena Yiangou, Chryssoula Thodi, Fofi Constantinidou
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