TY - JOUR AU - Mansor, Nur Izzati AU - Azmi, Nuratiqah AU - Ling, King Hwa AU - Rosli, Rozita AU - Hassan, Zurina AU - Nordin, Norshariza PY - 2019/03/23 Y2 - 2024/03/29 TI - Prospective stem cell lines as in vitro neurodegenerative disease models for natural product research JF - Neuroscience Research Notes JA - Neurosci Res Notes VL - 2 IS - 1 SE - Mini-Review DO - 10.31117/neuroscirn.v2i1.25 UR - https://neuroscirn.org/ojs/index.php/nrnotes/article/view/25 SP - 16-30 AB - <p>The use of <em>in vitro</em> model for screening pharmacological compounds or natural products has gained global interest.&nbsp; The choice of cells to be manipulated plays a vital role in coming up with the best-suited model for specific diseases, including neurodegenerative diseases (ND). A good <em>in vitro </em>ND model should provide appropriate morphological and molecular features that mimic ND conditions where it can be used to screen potential properties of natural products in addition to unravelling the molecular mechanisms of ND.&nbsp; In this mini review, we intend to demonstrate two prospective stem cell lines as the potential cell source for <em>in vitro</em> ND model and compare them to the commonly used cells.&nbsp; The common source of cells that have been used as the <em>in vitro</em> ND models is discussed before going into details talking about the two prospective stem cell lines.</p> ER -