Neuroscience Research Notes

ISSN: 2576-828X



Epilepsy is a chronic neurological disorder which affects people of all ages. Approximately 70 million people globally are suffering from epilepsy. Nearly 80% of the epileptic population live in low- and middle-income countries. The quality of life is greatly affected by comorbid conditions of epilepsy which include neurological, neurobehavioral and neuropsychiatric disorders.

Comorbidities in epilepsy are common yet ineffectively comprehended and frequently stay unaddressed. The prevalence of comorbid conditions is impressively higher in epilepsy than found in the all-inclusive community and other chronic conditions. There is a wide spectrum of secondary disorders that have a marked impact on the quality of life and burden of the primary epilepsy condition.

The aim of this research topic is to highlight basic, clinical and interdisciplinary research related to epilepsy and its comorbidities. We are pleased to invite Research Notes (Original research), Technical Notes, Case Notes, Mini Review, Hypothetical Papers and Views (Commentary) articles that summarize current knowledge, and point out gaps in understanding of epilepsy-associated comorbidities and related research for drug discovery. This special topic is focusing on but are not limited to the following specialties:

  • Experimental models of epilepsy and related comorbidities
  • Epilepsy associated neurobehavioral comorbidities like cognitive decline, dementia, anxiety, depression, etc.
  • Mechanisms of epileptogenesis and comorbidities
  • Clinical reports on epilepsy associated neurobehavioral comorbidities
  • Therapeutic and Molecular targets and approaches


Submission: 28 July 2018 – 31 December 2018
Review, Revision, Acceptance: Before 28 February 2019
Published: 30 March 2019


MOHD. FAROOQ SHAIKH | Monash University Malaysia, MALAYSIA

Dr Mohd. Farooq Shaikh is actively involved in neuropharmacological research. His personal interest is experimental epilepsy and the discovery of anti-epileptic drugs. His research approach involves pharmacology, biochemistry, behavior and gene expression techniques using in-silico, in-vitro and in-vivo studies. Currently his team is working on epilepsy and Alzheimer’s disease related cognitive dysfunctions like learning and memory. He is regional representative for Young Epilepsy Section (YES) of International League Against Epilepsy (ILAE).

CHRISTOS PANAGIOTIS LISGARAS | Albert Einstein College of Medicine, Bronx, NY, USA

Dr. Lisgaras research has mainly focused on the long-term consequences of early-life seizures on the adult brain cholinergic neurotransmission and interictal high frequency oscillations. His current research endeavors are mainly focused on post-traumatic EEG abnormalities and antiepileptogenic treatments in a rat model of traumatic brain injury under the Center Without Walls, NIH-funded consortium “Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx)”. He is a member of Next Generation Task Force of the International League against Epilepsy (ILAE), Vice chair for Research and Chair of the Research and Translational Task Force of the ILAE Young Epilepsy section.

KHENG SEANG LIM | University of Malaya, MALAYSIA

Professor Dr. Lim Kheng Seang, a University of Malaya (Malaysia) graduate, is a Professor of Neurology in Faculty of Medicine, University of Malaya and Consultant Neurologist specialized in epilepsy in University of Malaya Medical Centre and University Malaya Specialist Centre, Malaysia. He has been trained in the University of Malaya for his neurology subspecialty training, followed by fellowship training in Melbourne and Cleveland for epilepsy. He is currently the member of Malaysian Epilepsy Council and the president of the Malaysian Epilepsy Society and Malaysian Society of Neurosciences. Internationally, he is the chair of the Research Commission in International Bureau of Epilepsy and the Research Task Force in the Commission of Asian and Oceanian Affairs, International League Against Epilepsy.

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